GLP-1 Companion®
A 3-in-1 formula with digestive enzymes for proteins, fats and carbohydrates, probiotics for lasting regularity, and bromelain + papain for post-meal comfort.
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Made in USA
Gastric Enzyme Complex
Clinically proven benefits
Clinically proven benefits
- Stops sulfur burps and nausea at the source — not downstream
- Relief within 30–60 minutes of your first dose
- Ends the constipation/diarrhea cycle over 2–4 weeks
- Replaces Gas-X, Pepto, ginger, and enzymes in 2 capsules
- Zero fermentable fiber — won't aggravate your already-slowed system
Key ingredients
Key ingredients
Makzyme-Pro™ 2500 HUT / 400mg - Clinically standardized enzyme blend. Pre-digests stagnant proteins before fermentation.
Bromelain 90 GDU - The science behind the pineapple remedy your GLP-1 forum discovered.
Papain 2670 TU - Targets dense proteins causing sulfur gas.
Alpha-Galactosidase 300 GALU - Eliminates gas from vegetables, beans, and carbs. Unique in this category.
Tri-Probiotic Blend L. acidophilus + L. casei + L. plantarum - Restores motility. Ends the diarrhea/constipation cycle.
How and when to take ORYN
How and when to take ORYN
Take 1 capsule 20–30 minutes before your two main meals. 2 capsules per day.
Works with any GLP-1 injection schedule — weekly or daily. Enzyme relief within 30–60 min. Probiotic benefit builds over 2–4 weeks.
Safe with my medication ?
Safe with my medication ?
Yes. ORYN contains zero fermentable fibers, zero stimulants, and no known drug interactions with Ozempic, Wegovy, Mounjaro, or Zepbound. Safe to take alongside any GLP-1 injection on any schedule.
Shipping & 60-Day Guarantee
Shipping & 60-Day Guarantee
We know you need relief yesterday.
Dealing with GLP-1 side effects is exhausting, which is why we don't make you wait.
- Fast Delivery: Orders arrive in 2 to 4 business days anywhere in the US.
- Shipped from the USA: Proudly manufactured and dispatched directly from our US-based facilities (no overseas delays).
- Shipping Cost: FREE shipping on all Subscriptions AND 3-Month / 6-Month bundles. (A small flat rate applies only to single-bottle, one-time purchases).
60-Day Money-Back Guarantee: Not feeling relief? We'll refund every penny — no questions, no return needed.
94% saw significant GI improvement in clinical trials.
Here's what that actually feels like.
Honestly, I was ready to throw in the towel.
"honestly i almost gave up on wegovy because of this. the bloating got so bad i started dreading meals, not even hungry anymore just scared of what came after. my doctor kept telling me its normal just part of the process, push through it. i wasnt about to just push through it for another year so i went looking myself and found oryn through some pineapple trick thing going around. two capsules before i eat, thats literally it, and within a week the sulfur burps were just... gone. still mad it took me four months to find this"
The weight came off but my life didn't
"Down quite a bit of weight after four months on Wegovy, which is great, but every meal left me bloated for hours afterward. That part nobody warns you about. A friend in my GLP support group recommended ORYN, it's an enzyme and probiotic blend, two capsules before eating. Started noticing a difference within the first days. My stomach finally feels normal again, which honestly matters more to me at this point than the number on the scale."
Food just sat there. Then nothing moved.
"Nausea. Burps. Constipation. Ozempic gave me all three. Almost quit over it. Tried ORYN two weeks ago. Things move now. Meals don't feel like a punishment anymore. That's really it."
How ORYN works — and when.
-
Hour 01
Enzyme Intervention
Your stomach has been holding food hostage. ORYN's enzymes break it down immediately — proteins, fats, carbs — before they ferment into gas and nausea. The cleanup starts before you leave the table.
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Day 03-05
Gastric pressure reduces.
Less gas building up. Fewer sulfur burps. Your stomach empties the way it's supposed to. You eat dinner and just... move on with your evening.
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Day 14
Your Gut Bacteria Rebuild
Three probiotic strains start recolonizing your gut. The random diarrhea and constipation cycles out. Your digestion becomes something you can predict again.
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Day 30
You Feel Human Again
Enzymes at every meal. Probiotics working around the clock. Fast relief and long-term repair — running together, every day. That's the biphasic effect. You stay on your medication. You stay on track.
You're not weak. Your stomach was chemically stopped.
GLP-1 medications reduce gastric motility by design. It's not a side effect — it's the mechanism. And no one told you what to do about it.
0%
of GLP-1 patients quit within the first year.
Most say: "it made me sick."
0%
gastric retention at 4 hours.
Clinical gastroparesis threshold is 10%.
0%
of patients experienced GI side effects
for 2 full years — without relief.*
*Based on pooled data from the STEP 1–5 trials and the SELECT cardiovascular outcomes trial (n=17,604).
CLINICALLY FORMULATED
Not a gut supplement. A GLP-1 companion.
Your gut changed. Your supplement should too.
Your gut changed. Your supplement should too.
GLP-1 medications slow gastric emptying by design. Most digestive supplements don't account for this, they were formulated for a gut that moves food at normal speed. ORYN is built around slowed motility: fast-acting enzymes that break food down before it ferments, not after.
The Biphasic Action Formula — enzymes now, probiotics for the long term
The Biphasic Action Formula — enzymes now, probiotics for the long term
Most supplements do one thing. ORYN does two: Makzyme-Pro™, Bromelain, and Papain attack food breakdown within 30 minutes. Three probiotic strains (L. acidophilus, L. casei, L. plantarum) rebuild the gut flora that months of slow digestion have disrupted. Immediate relief and long-term repair — in one capsule.
Designed around your shot — not adapted for it
Designed around your shot — not adapted for it
ORYN was formulated specifically for the digestive pattern GLP-1 medications create: delayed gastric emptying, reduced motility, altered gut microbiome. Not a generic enzyme blend with a new label. The formula addresses the mechanism, not just the symptoms.
No fiber. No laxatives. No urgency.
No fiber. No laxatives. No urgency.
Fiber supplements worsen bloating when gastric emptying is already slow — your gut can't process what it can't move. Laxatives create urgency and dependency. ORYN uses zero fiber and zero stimulant laxatives. It works with your slowed gut, not against it.
The only formula built for GLP-1 digestion.
Most supplements weren't designed for a stomach that's been chemically slowed. ORYN was.
|
Others | |
|---|---|---|
| GLP-1 specific formulation | ||
| Biphasic action — fast relief + long-term repair | ||
| Zero fermentable fibers | ||
| Works in 30 minutes | ||
| Probiotic gut repair | ||
| Safe alongside all GLP-1 medications |
•
Formulated for GLP-1-induced gastroparesis
•
6 enzymes. Every macronutrient covered.
•
Immediate relief + long-term gut normalization
•
Safe alongside all GLP-1 medications
•
Formulated for GLP-1-induced gastroparesis
•
6 enzymes. Every macronutrient covered.
•
Immediate relief + long-term gut normalization
•
Safe alongside all GLP-1 medications
•
Formulated for GLP-1-induced gastroparesis
•
6 enzymes. Every macronutrient covered.
•
Immediate relief + long-term gut normalization
•
Safe alongside all GLP-1 medications
•
Formulated for GLP-1-induced gastroparesis
•
6 enzymes. Every macronutrient covered.
•
Immediate relief + long-term gut normalization
•
Safe alongside all GLP-1 medications
Your questions. Straight answers.
We built ORYN for one specific problem.
Here's everything you need to know.
How is ORYN different from a regular probiotic?
How is ORYN different from a regular probiotic?
Most probiotics add fermentable bacteria into a stomach that's already moving too slowly making bloating worse before it gets better. ORYN works differently. The enzymes act first, breaking down food before it ferments. The probiotics work downstream, restoring regularity over time. That sequence matters. It's why ORYN works from day one, while most probiotics take weeks just to settle in.
How soon will I feel a difference?
How soon will I feel a difference?
The enzymes activate within 30 minutes of your first meal. Most users notice a reduction in sulfur burps and post-meal heaviness within the first 3 days. Full biphasic effect — enzymes plus probiotics working together — is typically established by week 4. Take 1 capsule 20–30 minutes before your two main meals, every day.
Is ORYN safe to take with my GLP-1 medication?
Is ORYN safe to take with my GLP-1 medication?
Yes. Digestive enzymes and Lactobacillus probiotics are generally recognized as safe and carry no known interactions with GLP-1 medications. ORYN contains zero fermentable fibers — the ingredient class most likely to cause aggravation in a slowed GI tract. As always, inform your prescribing physician of any supplement you add to your regimen.
Do I need to take it with every meal?
Do I need to take it with every meal?
For best results, take 1 capsule before your two largest meals of the day. If you eat lightly — which many GLP-1 users do — once daily is sufficient. Consistency matters more than frequency. Daily use is what allows the probiotic component to rebuild gut motility over time.