Time to give your gut new life with the only enzyme complex built for GLP-1.
Our clinically standardized enzyme blend, delivering 2,500 HUT of protease activity to break down what your slowed stomach won't.
Biphasic Action Formula
Years of research
Formulated around the specific mechanism of GLP-1 — immediate enzyme action for relief, sustained probiotic support for long-term gut normalization.
6 Enzymes
Pharmacist formulated
Each enzyme selected to target a specific consequence of slowed gastric emptying — protein, fat, lactose, and fermentable sugars.
GLP-1 Specific
Targets delayed gastric emptying
GLP-1 medications slow stomach transit by design. Every enzyme in ORYN is selected to compensate for exactly that — breaking down protein, fat, and fermentable sugars before they stagnate.
The GLP-1 Companion Built for Your Gut
While traditional digestive enzymes treat general indigestion, ORYN targets the specific mechanism of GLP-1 medications — slowed gastric emptying. By combining our proprietary Makzyme-Pro™ enzyme complex with a targeted probiotic blend, ORYN delivers immediate relief and long-term gut normalization in a single formula.
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Others | |
|---|---|---|
| GLP-1 specific formulation | ||
| Biphasic action — fast relief + long-term repair | ||
| Zero fermentable fibers | ||
| Works in 30 minutes | ||
| Probiotic gut repair | ||
| Safe alongside all GLP-1 medications |
Find out why the experts trust Oryn™
"GLP-1 medications work by slowing gastric emptying. That is also exactly why patients develop sulfur burps, bloating, and food stagnation. The enzyme profile in ORYN addresses this directly. Bromelain and Papain accelerate protein breakdown, Fungal Lipase targets fat digestion, and Alpha-Galactosidase eliminates the fermentable sugars responsible for gas. This is the mechanistic gap that clinicians have been unable to fill with dietary advice alone."
"What I find clinically relevant about ORYN is the sequencing logic. The enzyme complex provides immediate pre-digestive support at the meal level, while the Lactobacillus strains work at the microbiome level over time. Most products address one or the other. The Biphasic Action approach is the correct framework for a patient whose GI transit has been pharmacologically altered."
"The patients most at risk of discontinuing their GLP-1 treatment are not those who fail to lose weight. They are those who cannot tolerate the gastrointestinal side effects. I recommend ORYN because it targets the actual mechanism — enzyme insufficiency caused by slowed gastric emptying — rather than simply masking symptoms. Retention on medication is where outcomes are won or lost."